Pure Biogenics utilizes ancient Chinese and Ayurvedic wisdom with the most recent advances in Western medicine. It has been scientifically formulated to reduce RLS symptoms.

For over 20 years, our state of the art laboratory has been providing the highest quality, all-natural ingredients and follows strict quality assurance guidelines. Our lab is a cGMP certified company, and holds a Drug Manufacturing License issued by the State of California Food and Drug Branch, and is registered as a Drug Establishment with the FDA.

Seratame’s unique formula relies on powerful ingredients backed by scientific studies:


Discovery 1: Magnesium Glycinate

magnesium malate for rls The latest medical research indicates that restless legs is likely a neurological disorder caused by malfunctioning dopamine receptors in the brain.1,2 Magnesium is thought to bind to aluminum3 and other toxins that clog these receptors, clearing the channel of communication for these receptors to begin working properly again and in turn, help address restless leg symptoms.

Discovery 2: Passionflower

passion flower restless legsA time-tested herb that has potent relaxation properties, making it highly effective for sleep. Passion flower extracts have been shown to aid in relaxation, and to alleviate occasional, but minor tenseness and restlessness.* Recent studies have show that passionflower may offer temporary support for nervousness and feelings of stress.* 

Discovery 3: Turmeric Extract

turmeric for rls Turmeric is one of the oldest & most utilized medicinal herbs in the world & the most recent research surrounding restless legs is all pointing towards inflammation as a possible cause. Clinical studies also show that curcumin phytosome is a powerful free radical scavenger, can help to support a balanced immune system response to normal metabolic stress, and can promote healthy joint mobility and flexibility.*

Discovery 4: Vitamin D3

Restless legs has been associated with vitamin D deficiency in several key studies, & restless legs severity has been inversely vitamin d3 restless leg syndrome relief vitamin e correlated with vitamin D levels.4 This is because vitamin D supports healthy dopamine levels in the brain & protects the brain from toxins that can cause an imbalance of dopamine levels. Vitamin D3 is the most effective and highest quality vitamin D that we’ve found at correcting any vitamin D imbalances in the body.

vitamin k2 rlsDiscovery 5: Vitamin K2

Vitamin K2 and D3 work together synergistically, increasing their effectiveness to transport calcium to your skeleton where it belongs & away from dangerous areas where it tends to accumulate such as arteries & blood vessels. There are several studies suggesting that many restless legs cases involve excess calcium within soft tissue cells & supplementing with vitamin K2/D3 has been shown to provide relief to restless legs patients.

Discovery 6: Probioticsrestless legs syndrome probiotics

The term “probiotic” is derived from the Greek and means “For Life.” This is a probiotic which targets and reduces harmful bacteria in the body, and is widely known to aid in the absorption of iron in the brain, also deficient in many restless legs sufferers. Because of its unique ability to synthesize nutrients for the body, we’ve found this to be the component that really ties together all of the ingredients found in Seratame, increasing the bio-availability for these ingredients, especially Iron, allowing for maximum absorption at the cellular level.


None of the ingredients in Seratame contains any of the major 8 allergens defined under FALCPA guidelines namely milk, eggs, fish (e.g., bass, flounder, cod), Crustacean shellfish (e.g., crab, lobster, shrimp), tree nuts (e.g., almonds, walnuts, pecans), peanuts, wheat, and soybeans.






  1. Systems genetics analysis of iron regulation in the brain. Leslie C. Jellen, John L. Beard, and Byron C. Jones,* http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742566/
  2. https://pubmed.ncbi.nlm.nih.gov/8363978/
  3. https://pubmed.ncbi.nlm.nih.gov/21273333/
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875352/